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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2C All Species: 31.52
Human Site: S430 Identified Species: 57.78
UniProt: Q06413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06413 NP_002388.2 473 51221 S430 S L S S C S S S Y D G S D R E
Chimpanzee Pan troglodytes XP_001139828 503 54271 S460 S L S S S S S S Y D G S D R E
Rhesus Macaque Macaca mulatta XP_001086412 483 52310 S440 S L S S C S S S Y D G S D R E
Dog Lupus familis XP_858441 472 51065 S429 S L S S C S S S Y D G S D R E
Cat Felis silvestris
Mouse Mus musculus Q8CFN5 474 51260 S430 D S L S S C S S S Y D G S D R
Rat Rattus norvegicus Q2MJT0 495 53235 S452 S L S S S S S S Y D G S D R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510456 503 54885 S460 S L S S C S S S Y D G S D R E
Chicken Gallus gallus Q9W6U8 499 53650 S456 S L S S S S S S Y D G S D R E
Frog Xenopus laevis Q03413 498 54053 P445 H E A T G R S P V D S L S S N
Zebra Danio Brachydanio rerio NP_571387 465 49956 S421 S L S S C G S S Y D G S D R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 A478 Y E G Y P Y R A L M G H N P R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 N225 E A H D R R T N E G E R E S P
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 F410 T Y V N N K T F F L K P P I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.4 93.3 99.1 N.A. 98.7 56.5 N.A. 93 63.1 56.6 79.4 N.A. 32.4 N.A. N.A. N.A.
Protein Similarity: 100 74.3 94.8 99.3 N.A. 99.7 69.2 N.A. 94 74.1 70.4 88.5 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 20 93.3 N.A. 100 93.3 13.3 86.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 20 93.3 N.A. 100 93.3 26.6 93.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 36.7 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 39 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 70 8 0 62 8 8 % D
% Glu: 8 16 0 0 0 0 0 0 8 0 8 0 8 0 54 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 8 0 0 0 8 70 8 0 0 8 % G
% His: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 62 8 0 0 0 0 0 8 8 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 0 8 0 0 8 0 0 0 8 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 16 8 0 0 0 0 8 0 62 16 % R
% Ser: 62 8 62 70 31 54 77 70 8 0 8 62 16 16 0 % S
% Thr: 8 0 0 8 0 0 16 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 8 0 8 0 0 62 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _